MedLumics’ new catheter is being evaluated in several ongoing pre-clinical studies. Results obtained in vitro and in vivo show the accuracy and reliability of MedLumics’ polarization sensitive low coherence reflectometry technology to evaluate catheter-wall distance, contact quality and tissue necrosis in real time. The discrimination between original and treated tissue is based on the detection of oriented collagen, which is an important component of the extra-cellular matrix of muscular fiber bundles in myocardium.
Supported by its proprietary optical miniaturisation technology, MedLumics is currently developing a clinical version of its catheter, comprising irrigation and multidirectional imaging.
- D. Herranz, J. Lloret, S. Jiménez-Valero, J.L. Rubio-Guivernau and E. Margallo-Balbás, “Novel catheter enabling simultaneous radiofrequency ablation and optical coherence reflectometry,” Biomedical Optics Express, Vol. 6, Issue 9, pp. 3268-3275 (2015).
- D. Herranz, J. Lloret, S. Jiménez-Valero, J.L. Rubio-Guivernau and E. Margallo-Balbás, “Percutaneous RF ablation guided by polarization-sensitive optical coherence reflectometry in an integrated catheter: experimental evaluation of the procedure,” The Journal of Innovations in Cardiac Rhythm Management, 6 (2015), 2086–2091.